U.S. stocks were lower, with the Nasdaq Composite falling around 100 points on Monday.

Shares of Nektar Therapeutics (NASDAQ:NKTR) rose sharply after the company announced results from a blinded 16-week treatment extension period in its Phase 2b REZOLVE-AA study.

The company said the REZOLVE-AA extension results demonstrated continued improvement in patients with severe-to-very-severe alopecia areata treated with rezpegaldesleukin, with responses strengthening over time across key SALT (Severity of Alopecia Tool) measures.

Nektar Therapeutics shares climbed 18.8% to $100.88 on Monday.

Here are some other big stocks recording gains in today’s session.

  • AEVEX Corp (NYSE:AVEX) shares jumped 40% to $37.70. The shares gained momentum from the recent debut of the company on the NYSE.
  • Compass Pathways PLC (NASDAQ:CMPS) gained 38.3% to $9.14 after President Donald Trump issued an executive order on Saturday instructing health regulators to hasten the review process of psychedelic drugs.
  • AtaiBeckley Inc (NASDAQ:ATAI) rose 30.6% to $5.26 after President Donald Trump issued an executive order on Saturday instructing health regulators to hasten the review process of psychedelic drugs.
  • GH Research PLC (NASDAQ:GHRS) gained 27.7% to $23.44.
  • POET Technologies Inc (NASDAQ:POET) gained 21.6% to $8.83.
  • Sila Realty Trust Inc (NYSE:SILA) gained 19.1% to $30.40 as the company agreed to be acquired by affiliates of Blue Owl for $2.4 billion.
  • TopBuild Corp (NYSE:BLD) jumped 16% to $475.80 after the company announced it will be acquired by QXO.
  • Innventure Inc (NASDAQ:INV) gained 14.3% to $5.26. Accelsius announced general availability of NeuCool® IR150 and launched NeuCool HyperStart program at Data Center World 2026.
  • Maxlinear Inc (NASDAQ:MXL) gained 11.6% to $29.31.
  • Kaspi.kz AO – ADR (NASDAQ:KSPI) surged 10.3% to $93.63 after the company announced that Tencent,Co-Founder and CEO Mikheil Lomtadze, key members of the senior management team and long-term institutional investors have completed the purchase of 6 million American Depositary Shares from Baring Fintech Venture Funds.
  • Hims & Hers Health Inc (NYSE:HIMS) gained 9.6% to $31.59.
  • Legend Biotech Corp (NASDAQ:LEGN) gained 9.5% to $23.18.
  • Globalfoundries Inc (NASDAQ:GFS) rose 7.9% to $59.06.
  • BlackBerry Ltd (NYSE:BB) gained 7.5% to $5.22. The company announced an expanded collaboration with NVIDIA Corporation (NASDAQ:NVDA) and a new automotive software deal with Leapmotor.
  • Hertz Global Holdings Inc (NASDAQ:HTZ) rose 6.1% to $7.88.
  • Wix.Com Ltd (NASDAQ:WIX) gained 5.7% to $72.14.
  • Veeco Instruments Inc (NASDAQ:VECO) surged 5.6% to $45.41.

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