HUTCHMED (China) Limited ("HUTCHMED") (Nasdaq/AIM: HCM; HKEX: 13) today announces positive high-level results from the SANOVO China Phase III trial in treatment-naïve patients with locally advanced or metastatic non-small cell lung cancer ("NSCLC") whose tumors harbor epidermal growth factor receptor ("EGFR") mutation and MET overexpression. ORPATHYS® (savolitinib) plus TAGRISSO® (osimertinib) demonstrated a statistically significant and highly clinically meaningful improvement in progression-free survival ("PFS") versus TAGRISSO® alone in both the high MET and intention-to-treat ("ITT") patient populations.

In both patient populations, the combination also demonstrated a very encouraging clinical benefit in overall survival ("OS"), a secondary endpoint of the trial. The trial will continue to follow-up on these results. These data will be presented at a forthcoming medical meeting.