On Tuesday, Exagen (NASDAQ:XGN) discussed second-quarter financial results during its earnings call. The full transcript is provided below.
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Summary
Exagen Inc. reported record quarterly revenue of $19.9 million, up 16% year over year, marking the highest revenue in company history. The company also achieved record AVISE test volume and pharma services revenue, while narrowing adjusted EBITDA loss to $0.1 million, nearing breakeven.
Exagen raised its full-year 2026 revenue guidance to $72 to $75 million, driven by strong execution and strategic focus on expanding product adoption, increasing ASP, and continuous innovation to address unmet clinical needs.
The company reported a significant increase in clinical adoption, with AVISE CTD test volume reaching nearly 39,000 tests, up 11% year over year. Trailing 12-month ASP increased to $446, marking the 13th consecutive quarter of growth, supported by enhanced revenue cycle management, including the use of AI for process optimization.
Pharma Services revenue exceeded $1 million in the quarter, reflecting ongoing expansion and the value of Exagen's unique data and biobank capabilities. The contract backlog also grew to over $6 million.
Exagen is on track for the commercialization of its new Myositis offering in early 2027, with plans to release a new product approximately every 12 months thereafter.
The company reported a gross margin of over 61%, up 90 basis points from last year, and operating expenses were managed efficiently, reflecting a significant improvement in operating leverage.
Management highlighted the company's progress towards sustainable profitability, with the expectation of reaching adjusted EBITDA breakeven at around $80 million in annual revenue.
Full Transcript
OPERATOR
Greetings and welcome to the Exagen Inc. Q2 2026 earnings call. At this time, all participants are in a listen-only mode. A brief question-and-answer session will follow the formal presentation. Should anyone require operator assistance during the conference, please press star zero on your telephone keypad. As a reminder, this conference is being recorded. It is now my pleasure to introduce your host, Tina Jacobsen, Investor Relations. Thank you.
You may begin.
Tina Jacobsen, Vice President, Investor Relations
Thanks, operator. Good morning, and thank you for joining us to discuss Exagen's financial results for the quarter ended June 30, 2026. Today I'm joined by John Abali, our President and Chief Executive Officer, and Jeff Black, our Chief Financial Officer. The recording of this call, the press release announcing our financial results, and a slide presentation can be accessed on our website at www.exagen.com. Today's call will include forward-looking statements.
We encourage you to review the statements contained in today's press release and the risks and uncertainties described in our SEC filings, which identify certain factors that may cause the company's actual events, performance, and results to differ materially from those contained in the forward-looking statements made on today's call. We also will discuss non-GAAP financial measures on this call. Descriptions of these non-GAAP financial measures and the reconciliations of GAAP to non-GAAP financial measures are included in today's press release.
And now I will turn the call over to John Abali.
John Abali, President and Chief Executive Officer
Good morning everyone, and thank you for joining us today. The second quarter was an outstanding one at Exagen, and there's a lot to be excited about, so I'll get right into the details. This morning we reported revenue of $19.9 million, up 16% year over year and the highest quarterly revenue in company history. And while total revenue was a record, we also achieved several other records in the quarter including quarterly AVISE test volume, trailing 12-month ASP, and pharma services revenue.
We delivered those top-line achievements while narrowing adjusted EBITDA loss to $0.1 million, essentially breakeven and a significant improvement compared to the $1.7 million loss in the second quarter of last year. Based on the strength of the first half of 2026, we are increasing full-year revenue guidance to $72 to $75 million. Results like these don't happen by accident. They reflect execution against the same three core objectives we've prioritized for the last several years: first, expanding adoption of our products; second, increasing ASP through disciplined revenue cycle management; and third, delivering a steady cadence of innovation to address the unmet needs of our clinicians. In our business, individual quarters will always have some variability, but the structural changes we've made are clearly improving our long-term trajectory of both volume and ASP. Q2 was the strongest demonstration yet that our strategy is working and our business can scale. As always, we anchor to our mission.
Autoimmune disease is diagnosed too late and too inconsistently, and it's the patients that suffer. Exagen exists to bring clarity to that complexity. We have now surpassed 1.2 million AVISE CTD results delivered to clinicians and their patients since product inception. That's a meaningful milestone, but we're just getting started. With just over 3% share of an autoimmune testing market we estimate at more than $2.2 billion and growing about 5% annually, the opportunity ahead of us is significant.
We intend to continue to earn share the same way we built trust in this underserved channel: through the best science, more timely answers, and world-class service. Let me start with clinical adoption. AVISE CTD volume reached nearly 39,000 tests in the second quarter, up 11% year over year and the highest quarterly volume in Exagen's history. I also want to put that volume record in context. In 2023 we deliberately reset our ASP strategy and rebuilt our commercial approach, accepting that volume would contract.
As a consequence, this quarter volume exceeded those previous levels, and we crossed that threshold with a trailing 12-month ASP nearly 40% higher than it was back then. We established the right strategy, executed with discipline, and have now rebuilt the volume base on a dramatically stronger economic foundation. The quality of that growth is exactly what we want to see. Over 2,800 clinicians ordered AVISE CTD in the quarter, up approximately 9% year over year, which speaks to the value our testing has established within the rheumatology community.
Sales force productivity reached record levels with trailing 12-month AVISE CTD revenue per territory of over $1.4 million in the second quarter. This is compared to roughly $1.3 million for the full year 2025. The investments we've made to upgrade, expand, and enhance the training of our sales organization are delivering. We continue to advance the clinical aptitude of the team, and the momentum is carried into the current quarter. Turning to ASP.
Trailing 12-month ASP is the metric we use as operators to assess the performance of our business. Because it smooths the variability associated with accrual accounting and the timing of collections, we believe it's the most reliable indicator of progress in what is a highly critical area of our business. In the second quarter, trailing 12-month ASP expanded to $446, up $18 per test, or 4% versus last year, and marking our 13th consecutive quarter of growth.
Our revenue cycle team deserves recognition for another quarter of strong collections, including meaningful recoveries on older claims. The performance reflects years of disciplined work to structurally improve how this team operates. This year our revenue cycle strategy has shifted more towards optimization of our processes. We're leveraging analytics and AI to prioritize where the highest-value opportunities lie, to automate appeals, and to streamline medical record extraction.
Together these initiatives have driven trailing 12-month ASP from $284 at the end of 2022 to $446 today, and I'm confident there's more ground to gain. Pharma Services also delivered a record quarter, with quarterly revenue crossing the million-dollar point for the first time. This is a business we've built deliberately over the past couple of years, and the strong results are early proof that the unique data, biobank, and scientific capabilities we've assembled serve not only clinicians but also partners developing the next generation of autoimmune therapies.
During the quarter we began to build on the success we've achieved in incorporating AI across RCM processes by investing in the development of customer-facing applications. This AI-powered commercial infrastructure is designed to deepen clinical engagement, support AVISE utilization, and embed Exagen directly in the rheumatology workflow. It's early, and we'll share more as development progresses, but over time we believe the investment will complement our commercial team and reinforce Exagen's leadership within autoimmune diagnostics.
On the evidence front, we published a systematic review validating real-world AVISE Lupus performance. This manuscript is one of the most extensive evidence-generation efforts behind any novel lupus diagnostic, pooling years of data representing 3,100-plus patients across 14 medical centers into the most diverse analysis of the AVISE test to date. Most notably, AVISE Lupus identified approximately 25% of SLE patients who are missed by conventional markers, and this was noted by the authors, including some of the most prominent lupus physicians in the space.
AVISE meaningfully influences diagnosis, physician confidence, and patient management. This is the kind of clinical impact we strive to deliver across our portfolio, and this manuscript helps make the impact clear. And on that note, our innovation engine remains on track. Our Myositis offering, the first new standalone product for Exagen in many years, continues to progress towards commercialization in early 2027, and we remain committed to a cadence of approximately one new product every 12 or so months thereafter.
We've deliberately built an R&D-to-commercial machine that can deliver on that cadence, and our channel is eager for what's to come. Before I hand it over, I want to take a second to highlight the immense progress we've made. In 2022 our full-year adjusted EBITDA loss was around $40 million and worsening. This quarter we approached breakeven adjusted EBITDA while setting records across the business, and we did it before our next wave of products has even launched.
This is what disciplined execution compounds into: a business that grows, innovates, and generates cash. Sustained profitability is within reach, and we intend to cross that threshold through the same disciplined execution that brought us here, delivering on our commitments and building a durable long-term organization. With that, I'll turn it over to Jeff for additional comments on the financials.
Jeffrey G. Black, Chief Financial Officer
Thank you, John, and good morning, everybody. As John just highlighted, our second quarter results reflect another strong quarter of execution across the business. We achieved record top line performance driven by record testing volume and trailing 12-month ASP and a record contribution from our Pharma Services offering. Starting with revenue, we generated $19.9 million in the second quarter, an increase of 16% year over year and 15% sequentially.
Avise CTD test volume grew 11% year over year reflecting continued strength in clinician adoption and utilization as well as the impact of last year's investment in commercial expansion. Our commercial investments are delivering solid returns even with several sales territories under one year old. Productivity continued to ramp up. Trailing 12-month CTD revenue per territory grew about 6% year over year and ordering clinicians increased approximately 9%.
Avise CTD trailing 12-month ASP expanded to $446 per test, up 4% compared to last year. Execution of our revenue cycle management initiatives supported a strong in-period ASP result, which included over $1 million collected from claims older than 360 days. Notably, our total cash collections in the first half of 2026 exceeded first half 2025 levels by $9 million. Over time, we continue to target an ASP of at least 50% of our Medicare reimbursement, or approximately $600 to $650 per test, recognizing this will take time and that quarterly contribution from our revenue cycle initiatives can be variable.
Pharma Services generated revenue of just over a million dollars in the second quarter, up over 200% compared to the second quarter last year, reflecting continued execution against contract backlog and broadening contribution from this offering. To put our 2026 performance in perspective, in 2024 we generated just over $100,000 in full-year Pharma Services revenue, growing to $1.7 million in 2025 and now to $1.3 million in only the first half of 2026.
At the same time, we grew our contract backlog in Q2 by about a million dollars to over $6 million. And while revenue recognition from this business can fluctuate significantly from quarter to quarter, we see this as another long-term growth lever with the trend line tracking positively. Moving to gross margin, we reported just over 61% for the second quarter, up approximately 90 basis points compared to last year. Gross margin in the quarter benefited from ASP expansion, operating leverage and ongoing COGS rationalization that has streamlined workflows in the lab and reduced costs across our supply chain.
We remain confident that gross margin will progress to the mid-60s over time as we achieve further ASP expansion, generate additional scale and fixed-cost leverage, and further optimize costs. Turning to expenses, total operating expenses for the second quarter were just under $14 million, or approximately 70% of revenue, a significant improvement compared to 75% in the second quarter last year. And this performance reflects the operating leverage inherent in our model.
We delivered 16% revenue growth while holding opex growth to 7%. While opex levels will vary from quarter to quarter, that kind of discipline will continue as we scale even with planned investments in the R&D pipeline. Note that second quarter opex included non-cash stock-based compensation of about a million dollars, an increase of over half a million versus the second quarter last year. Breaking out the components of opex, second quarter SG&A was $12.5 million, an increase of just under a million dollars compared to second quarter 2025, driven primarily by increased stock-based compensation and investment in commercial talent and territory expansion.
R&D was $1.4 million in the second quarter, down modestly compared to last year due primarily to timing of investments, while continuing to support pipeline development including the preparation for our myositis product launch expected in early 2027. Adjusted EBITDA loss, which excludes depreciation and non-cash stock-based comp expense, improved significantly at a loss of just over $100,000 in the second quarter compared to a $1.7 million loss in the second quarter last year.
While we don't expect adjusted EBITDA to sustain at this level in 2H26, this quarter's roughly $20 million in revenue and near-breakeven adjusted EBITDA are strong proof points for our operating model that demonstrate the leverage we believe the business will deliver as we scale. Turning to the balance sheet. We generated $3.1 million in cash in the second quarter, ending the period with cash, cash equivalents and restricted cash of just under $25 million.
This improvement reflects the rebound following heavy cash use in the first quarter associated with our revenue cycle management process where we hold claims in the first quarter of the year, with $37 million in cash and accounts receivable at June 30th. We continue to believe that our balance sheet provides a runway needed to support the business to reach sustainable adjusted positive EBITDA and positive free operating cash flow. Shifting to guidance, today we raised our 2026 revenue outlook to reflect strong execution-driven first half performance.
We now expect full-year revenue of $72 to $75 million, up from our previous guide of $70 to $73 million. Our updated outlook continues to assume high single-digit volume growth for the full year, reflecting improved revenue cycle management performance in the first half, supporting a full-year mid-single-digit ASP growth compared to our Q4 2025 ASP exit rate. Our guide also incorporates the seasonality impact we typically experience in the second half of the year.
In closing, our second quarter results are a clear demonstration of the scale and leverage we've committed to building and reinforce our view that the business is positioned to reach adjusted EBITDA breakeven at around $80 million in annual revenue. With that, operator, we will now open the call for questions.
OPERATOR
Thank you. We will now be conducting a question-and-answer session. We ask that you please limit yourselves to two questions each in order to accommodate everyone. If you would like to ask a question, please press star one on your telephone keypad. A confirmation tone will indicate your line is in the question queue. You may press star two if you would like to remove your question from the queue. For participants using speaker equipment, it may be necessary to pick up your handset before pressing the star keys.
One moment, please. While we poll for questions, the first question is from Dan Brennan from TD Cowen. Please go ahead.
William, Analyst at TD Cowen
Hi, this is William on for Dan. So guidance was raised by $2 million at the midpoint. Is there any reason there isn't a fair amount of conservatism baked here on both ASP and volumes? Last year you did see a sequential uptick in volumes from 2Q to 3Q. So just trying to understand if there's conservatism in there.
John Abali, President and Chief Executive Officer
Thank you. Hey William, good morning. Thanks so much for the question. Very valid. Our thinking on this is for Q2, you know, we had a very nice quarter and relative to our original projections we're a couple million above where we expected to be. The second half of the year, you're right, last year we had a phenomenal second half which didn't have the typical seasonality. It was relatively flat compared to our Q2 but wasn't down. You know, we had 10 years of seasonality prior to that.
And so I think from our standpoint, just keeping that in the back of the mind is an important factor as we crafted our guidance this time around.
William, Analyst at TD Cowen
Got it. And then how should we expect salesforce expansion contribution to volumes in the second half? Are you expecting any contribution there?
John Abali, President and Chief Executive Officer
Well, we definitely expect contribution. We're putting a lot of investment into those folks and we're actually really excited about the caliber of individuals that we've been able to find and attract to our company. I know we've spoken in the past, but I sit in on the interview of anyone who comes into the company, especially on our sales organization, and man, we really have some fantastic folks. They're actually here doing some training this week as well, or a few of them are.
So our investments in that group remain very strong and we have, I think, certainly the best autoimmune sales force out there. So therefore we expect pretty decent contribution. But most of these expansion territories were starting from relatively low bases and so it'll take a little bit of time before they really move the top line number in a meaningful way. But over time, call it the next 9–12 months, I think that 10% expansion in our sales force that we executed in the back half of last year should really start to drive some meaningful volume growth for our organization.
OPERATOR
The next question is from Bill Bonello from Craig-Hallum Capital Group. Please go ahead.
Bill Bonello, Analyst at Craig-Hallum Capital Group
Hi guys. Thanks. First one is just a simple housekeeping question. Can you give us the Avise revenue for the quarter?
Jeffrey G. Black, Chief Financial Officer
Yeah. Good morning, Bill. Thanks so much for the question. So Avise CTD revenue for the quarter was $17.7 million.
Bill Bonello, Analyst at Craig-Hallum Capital Group
Perfect. That is what we calculated, but wanted to be sure we were doing it right and then just can you talk to us today? Great to see the progress on ASP. Just trying to get a sense of where you're at in terms of getting paid for some of the new markers that you've launched. You know, to what extent the improvement that we've seen in ASP is more related to, you know, revenue cycle management versus, you know, opportunity in front of us on getting paid for additional markers.
Jeffrey G. Black, Chief Financial Officer
Sure. Bill, this is Jeff Black. Thanks for the question. Appreciate you participating in the call. I'll answer a couple different ways. I think we're starting to really look at the ASP on a blended basis across the entire Avise CTD panel. I know we've communicated in the past what our expectation was on the new biomarkers, so we'll certainly share that with you. Combined, T cell, RA33, and PAD4, our overall expectation we'd communicated was going to be somewhere in that $100 range.
Where we're tracking today is really in the mid-90s, so we're tracking very well. We don't think there's any reason we couldn't ultimately get to that target, particularly since a lot of those claims from the last year are still going through appeals and revenue cycle management. So we're encouraged by the traction. It has been a contributor. Like I said, it's in that mid-90s range and tracking very well.
OPERATOR
Thank you. Thanks, Bill. The next question is from Kyle Mixon from Canaccord Genuity. Please go ahead.
Kyle Mixon, Analyst at Canaccord Genuity
Hey guys, thanks for the questions. Congrats on the great quarter. So had a multi-part guidance question on the components. So on ASP you raised that kind of guidance from, I think, low single-digit growth to now mid single-digit even though the trailing 12-month ASP was kind of flat quarter to quarter. So that's interesting. I'm just curious what you're seeing with just kind of collecting and the RCM benefit I think you were mentioning and then maybe some private or commercial payers, if any progress that you expect to help inflection maybe towards year end.
Then on the volume side I guess it just looks like roughly similar second half volumes to first half which I guess makes sense. But just looking at prior years, even though you have some seasonality factors like in the fall and November and so forth, just maybe, you know, just maybe just point to some areas of upside in volume specifically that we could, you know, hope for. Thanks.
John Abali, President and Chief Executive Officer
Yeah, thanks so much for the questions, Kyle, and for joining this morning. So just to kind of take these one at a time on the guidance side, you know, very proud now, 13 consecutive quarters of increasing ASP. That's not easy to do as I think you'll see across the industry. And I think it speaks a lot to the fact that we have the right strategy in place, the right team, and we're executing diligently and, as I tried to mention a second ago, really a ton of credit goes to our revenue cycle team.
They're firing on all cylinders. And I think the more exciting thing from our standpoint is we still have a lot of optimization that we're working into the process and feel very optimistic about the future as well. If you take a look at year over year, I believe we're up 4% on ASP. So I think we're tracking exactly as you said it. So low single digits is what we've communicated in terms of growth expectations year over year in the past. Progressing to mid single digits is what is baked into the guidance.
And, as we've said, projections on ASP improvement over time are always difficult to nail down timing and magnitude. So that's what we think is a reasonable expectation for us. Looking into the second half, the middle part of your question, progress with commercial payers continues to be very strong. You know our Medicare rate is static and so progress over the last 13 quarters has really been with our private payer groups, and we have been highly effective in our administrative law judge hearings, we've been very effective in our appeals efforts.
We've continued to develop evidence which substantiates our report, and our processes have improved materially over the last few years. So from our standpoint that trailing 12-month progression and improvement and growth is 100% attributable to progress with commercial payers. We tend to focus more on cash collections and the blended ASP rather than activity related to some of those individual payers. And my reason for that is I think that's what really matters.
And I also think that there can be a dislocation between activity and results over time. So that's what we try to point people to, that's what we've been consistent in communicating, and very proud of the way the teams have operated. The last part of your question related to volume: first half roughly equal the second half. I think you nailed that as well. Just keep in mind, second half tends to have less actual business days with a pretty strong slate of holidays coming in, especially in Q4.
We also tend to see from a physician standpoint, for some reason or another, the second half tends to be higher on vacations for our clinical group. So, you know, July through December we just end up functionally with less working days than we do typically see in the first half. And as I mentioned a little bit with a prior question, I think it's just important to recognize we have had seasonality in the business. Last year was a phenomenal year for us.
We're trying to honestly like hell to continue to grow the business in the second half and match what we did last year, if not exceed it. But at the same time I think you have to live in reality too. So hopefully that addresses each of your points.
Kyle Mixon, Analyst at Canaccord Genuity
Yeah, that was great, John, thanks so much. I'll give you a break. Maybe for Jeff on the framework on the path to break-even EBITDA, that has proven to be remarkably accurate. Basically this quarter you're at that 80 million run rate, just under the 63% gross margin. I guess though, going forward maybe you'll be close to the 80 million annualized run rate. But how should we expect gross margin to track? I think the last time we spoke it sounded like maybe high 50s, close to 60 for the rest of the year.
At this point it seems like maybe you could eclipse that.
Jeffrey G. Black, Chief Financial Officer
Yeah, Kyle, thanks for the question. Yeah, I think even last call, I think we had called 60% for 2026 more aspirational, right, and to think about it more in the high 50s. We actually think there's now a track to ending the year at that 60 or above. So we've seen very good traction. ASP expansion, done a really nice—excuse me—really nice job at managing fixed costs, managing supply chain costs. So I think the 60% range is a lot more realistic now and less aspirational for the year.
Kyle Mixon, Analyst at Canaccord Genuity
Okay, awesome. Thanks guys.
Jeffrey G. Black, Chief Financial Officer
Thanks, Kyle.
OPERATOR
The next question is from Max Masucci from Ross Capital Partners. Please go ahead.
Max Masucci, Analyst at Ross Capital Partners
Hi. Congrats on a strong print. First one, sales force productivity. The five territory reps you hired in 2025 I believe are beyond the six- to nine-month ramp. Just curious if those reps provided a noticeable boost to volume growth in Q2 or if the strength was more broad-based across the entire force. And it'd be great to know what's really driving the productivity higher, if you've adopted any new tools or strategies that are making an impact.
John Abali, President and Chief Executive Officer
Yeah. Good morning, Max. Welcome to the calls and happy to have you follow the story from a sales rep productivity standpoint. Great question. So trying to pick this apart a little bit. You know, we added five territories last year. One of those additions essentially split an existing territory, so you could argue you're kind of starting over a little bit. In six areas we see pretty decent distribution of productivity at this point in time. And we have one of our expansion territories has almost doubled in the time that we've added that group.
And then we're seeing kind of—right—consistent with our national growth on the, call it, the lower end of the growth profile for the expansion territories. So if that makes sense. So somewhere around 10%, 11% growth on the lower end of our expansion territories, up to 80%, 90% growth on our higher-end performing territory. So still broad. There are different reasons at play. Some of it has to do with potential, some of it has to do with ramp time for the individual learning curve of that rep.
But I think the great thing from our perspective is very confident in the people we have and over the last six to nine months—certainly proved out the—almost 12 months now—certainly proved out the thesis that the territories that we chose were the right areas to expand. And that's always a critical variable that you hope to get right and you don't know until you go back out and do it. So happy with that. We saw growth really across the entire nation.
So what's driving that? I think the refresh of the product last year with the addition of the new analytes certainly reinvigorated the sales force, but it also expanded our utility into rheumatoid arthritis where we had classically or historically been focused more on the lupus side. And that's a big deal, and I think you're seeing it play out. We saw it play out in the back half of last year with some of the momentum, and that really showed up here in Q2.
So very proud of the team. I've been in the field quite a bit, was actually in the field last week as well. We still have a lot of room to run. So our team is still working on getting that messaging out. We're still working on articulating the clinical value in a more precise and tailored way. And as I mentioned as well, our evidence generation efforts continues to mature. Our systematic review that we just had really refreshes some of the lupus clinical data and, you know, to be identifying 25% of patients missed by conventional serologies is a really big value for clinicians.
And so having that printed and out and able to market I think just in general is enhancing the clinical value of the product and our team is really pushing it. So more to come.
Max Masucci, Analyst at Ross Capital Partners
Great. And just a follow-up. So I think historically or more recently, about a third of your ordering clinician growth has come from outside of rheumatology, right—GPs, internists, OB/GYN, pulmonology. Just curious, is that becoming a deliberate sort of channel strategy and just how have the ordering trends for those types of docs compared to what you're seeing in rheumatology?
John Abali, President and Chief Executive Officer
Yeah, it's a really good question. We still see general 80/20 rule here that most of our business comes from our rheumatologist call point. Now at the same time you're right on in that referral network into rheumatology is finding a significant amount of utility with AVISE CTD, especially with the enhanced biomarkers, and I think multiple reasons at play there, but some of it, the workforce shortage within rheumatology is certainly lending to that.
I actually think that this will be very interesting as we launch myositis as well. That primary call point will be the rheumatologist. It'll keep it within our core sales channel, but it has applicability into pulmonology and some of the other subspecialties that manage these patients. And, you know, internally, as we look for further sales expansion, understanding what that outside room demand looks like is a pretty decent predicate for our next wave of expansion.
And so I think we'll know more here as we start 2027, but we're seeing pretty decent growth within some of these other specialties.
Max Masucci, Analyst at Ross Capital Partners
Great. Thanks team. Nice quarter.
John Abali, President and Chief Executive Officer
Thanks, Max.
OPERATOR
The next question is from Mark Massaro from BTIG. Please go ahead.
Mark Massaro, Analyst at BTIG
Hey guys, congrats on a strong quarter. I wanted to ask about the myositis launch. Can you just give us a sense for what we should be on the lookout for in terms of any data readouts, timing, and then can you give us maybe a sneak preview on how you're thinking about pricing the test?
John Abali, President and Chief Executive Officer
Yeah. Good morning, Mark. Thanks for the question. So very excited about the myositis opportunity. Just as a reminder for folks, this is the number one asked-for product amongst our rheumatologist clinical base. So when our team's in the field, and this is our product development team, our marketing team, our sales or myself, as we talk to our clinicians and ask them how we can better serve them, this comes up and it's not even close to the number two asked-for offering.
So really excited to be able to provide a comprehensive solution here for folks that we think will dramatically impact patient care and find folks at very high risk of some pretty dangerous clinical outcomes. So that development remains on track. By the way, we had to bring two new platforms into our laboratory, get those analytically validated. That's all occurred. We have to obviously get the sample cohorts to conduct clinical validation. All of that's in process and remains on track.
Very happy with the way the teams are executing there. And so we remain in line with our expectations to launch commercially in the first part of 2027. So pricing-wise, from our standpoint, we're going to launch similar to what we did with the analytes that we launched last year. And that is there's methodology-based CPT codes that correspond with the various analyte testing. So you would have ELISA-based testing, for example, has established CPT code.
That's all been vetted and we believe we have the right set of codes to bill this out. We don't have a significant track record of billing all these codes, and so as we launch from a revenue standpoint, we're going to mirror very close to cash collections and then over time establish that across rate and then we'll be able to set an expectation publicly as well. So that's how we'll launch for reimbursement. And we expect as our clinical validation matures, to be able to provide algorithmic interpretation and potentially pursue value-based reimbursement long term.
But that's going to be down the line. The initial launch will be with established CPT codes.
Mark Massaro, Analyst at BTIG
Yep, that makes sense. That's really helpful. And then you guys are making a lot of strides commercially with all the metrics you've provided. You're really knocking on EBITDA positivity here. On the other hand, you're basically saying that you can get to adjusted EBITDA break-even at $80 million of revenue. I guess my question is it looks like you could do it sooner than that. So how should we think about some of the factors that would lead you to not getting there before $80 million?
Is that investments you're making in the business? Maybe. Is there any way you can quantify some of those investments you're making in the business? Whether it's headcount or R&D? That would be really helpful.
John Abali, President and Chief Executive Officer
So if I understand the question, Mark, you're just saying what are the risks to reaching adjusted EBITDA positive. Why not a little bit sooner? Okay, great. Thanks for that question. I think it's absolutely relevant. So we're not guiding on adjusted EBITDA positivity. I think we're very close, obviously with the results that we turned in this quarter. You know, we're knocking on the door there. From our standpoint, second-half seasonality is going to come into play with hitting a sustained $20 million-plus revenue number on a quarterly basis. We're also right around the corner from a product launch.
So I don't think we're too far off. And, you know, whether we're plus or minus a quarter, we've got the balance sheet to get there and we just want to get there in a measured, sustainable fashion. And I think we've tried to grow the business, but with an eye towards profitability and that's what we've executed on for the last several years. So risks-wise there's always reimbursement risks that exist in this business. I guess, theoretically, you could also have some hit from a volume standpoint, a key client or something like that, but nothing's foreseen at this point in time.
And in fact, if anything, most of what we're seeing is very positive related to the efforts and energy that the team's executing against. So I think we're well on track and it should be around the corner.
Mark Massaro, Analyst at BTIG
Fantastic. And one last one. You guys have been collecting close to a million or a little over a million in prior period collections the last couple quarters. Obviously, you've made some good changes to revenue cycle management. Should we expect these initiatives to continue or at least to be able to collect from prior periods in the coming quarters?
Jeffrey G. Black, Chief Financial Officer
Yeah, Mark, this is Jeff. Yeah, I guess the way I would answer that, maybe flippantly, is, you know, as long as there's an appeals queue and, you know, we're focusing on revenue cycle management and maximizing, you know, the appeals process, then yeah, we do expect that we'll continue to see excess cash. That said, the better we do in any given quarter, we're kind of working against ourselves because that typically has an impact on the accrual rate.
So the better we do, the higher our accrual rate will go. And we try to be very conservative as much as we can about the accrual rate and not get ahead of ourselves. But the expectation is we're seeing really nice momentum. First half of this year, we collected about 2.3 million in cash greater than 360 days. Just to put that in perspective, I think a year ago for the full year was about 1.5 million, and in 24 is 2.7 for the full year. So we're tracking well ahead of historical trends.
Mark Massaro, Analyst at BTIG
Fantastic. Thanks, guys.
Jeffrey G. Black, Chief Financial Officer
Thanks, Mark.
OPERATOR
The next question is from Matthew Parisi from KeyBanc Capital Markets. Please go ahead.
Matthew Parisi, Analyst at KeyBanc Capital Markets
Hi. Congrats on the great quarter. This is Matt Parisi for Paul Knight at KeyBanc Capital Markets. I was wondering if you could give an update regarding the local coverage determination. Last we heard, there was an expectation of an update in mid to late 2026. Is that still the expectation?
John Abali, President and Chief Executive Officer
Hey, Matt, good morning. Thanks so much for the question. That is still our expectation, but we don't control it and it's a fairly opaque process. So just as a reminder where we sit now, we have a completed request in to MolDX. We've actually had that in since the summer of 2022 and are waiting for their feedback. Our reimbursement with Medicare continues to be very stable and no changes there, but still looking for that next step which would either be a CAC meeting or a draft LCD to come out.
So no update as of right now. We do, with the generation of this new systematic review, we're working to get that in front of the MolDX team and review it with them. So we maintain a very good relationship with that group, but no update now.
Matthew Parisi, Analyst at KeyBanc Capital Markets
Appreciate the insight. And then if I can ask one more, does Exagen expect to expand its sales force in advance of the Myositis launch or would the current salesforce be focused on both the ADVISE CTD test and then Myositis test?
John Abali, President and Chief Executive Officer
Yeah, great question. So we anticipate selling it concurrently with the ADVISE CTD offering along with the rest of our portfolio. So our existing sales force will go through training on the Myositis product here at the end of Q3 in anticipation of the launch. It will be available to all 45 territories and the clinicians within those territories. And like I said, it's a very consistent call point, primarily the rheumatologist with some applicability into the referral network.
It may have more applicability into the pulmonology space than, call it, CTD does currently, but we'll just have to figure that out over time and that won't be our initial push. So we'll stick within our existing customer base and offer it with our existing team. We do anticipate taking a look at sales expansion opportunities after the launch because we want to, depending on the uptake, that changes the opportunity rating essentially of each expansion opportunity.
So we'll get through that launch and then look for the next wave.
Matthew Parisi, Analyst at KeyBanc Capital Markets
That sounds great. Thanks for the questions.
John Abali, President and Chief Executive Officer
Thanks, Matt.
OPERATOR
There are no further questions at this time. I would like to turn the floor back over to John Abali for closing comments.
John Abali, President and Chief Executive Officer
Fantastic. And thanks so much. I really appreciate everyone joining the call today. This was about as fun as quarters get from my perspective. We had records in revenue, volume, trailing 12-month ASP, and pharma services revenue all delivered at essentially break-even adjusted EBITDA. That's been a milestone that's been a long time coming from my perspective. In fact, three years ago for our organization that combination would have sounded crazy, to be honest.
Our team made it a reality through consistent, disciplined execution and I'm really proud of the group here. The talent and character across Exagen continues to transform the organization into what I think is the preeminent diagnostic company serving autoimmune patients. And honestly, I'm as excited about the opportunity ahead of us as I've been since joining just a few years ago. We're within reach of the financial inflection we've been building toward.
And while others are focused elsewhere, we'll keep chipping away to build a truly incredible autoimmune powerhouse. We appreciate the support of all our stakeholders and look forward to updating you on our progress. Thanks again.
OPERATOR
This concludes today's teleconference. You may disconnect your lines at this time. Thank you for your participation.
Disclaimer: This transcript is provided for informational purposes only. While we strive for accuracy, there may be errors or omissions in this automated transcription. For official company statements and financial information, please refer to the company's SEC filings and official press releases. Corporate participants' and analysts' statements reflect their views as of the date of this call and are subject to change without notice.
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