PacBio (NASDAQ: PACB), developer of the world’s most advanced sequencing technologies, and TychoBio, an AI drug discovery company, today announced a collaboration to generate full-length RNA data that TychoBio will use to train models for RNA therapy design. Under the terms of the agreement, TychoBio plans to use PacBio HiFi sequencing and Kinnex long-read RNA sequencing to generate data from more than 10,000 samples, building large-scale datasets linking the design of steric blocking antisense oligonucleotides (SBOs) to their effects across the transcriptome, with plans to expand the approach to siRNA and other RNA-targeting compounds.