- Data on ALYFTREK in children ages 2 to 5 years demonstrate recovery of pancreatic function in some children –

- Additional abstracts on clinical and real-world evidence on CFTR modulators also presented -

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced new interim data from the ALYFTREK® (vanzacaftor/tezacaftor/deutivacaftor) 2 to 5 years old open-label extension study, highlighting recovery of exocrine pancreatic function in some children in that age group, allowing those children to discontinue pancreatic enzyme replacement therapy (PERT). Pancreatic exocrine insufficiency in children with cystic fibrosis (CF) was previously believed to be irreversible. These data were presented at the North American Cystic Fibrosis Conference (NACFC).