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5AM Venture Management, LLC
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $287,891,952
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- MAPLIGHT THERAPEUTICS INC · COM · 56565P103 · shares: $34,048,394
- TYRA BIOSCIENCES INC · COM · 90240B106 · shares: $32,875,778
- ENTRADA THERAPEUTICS INC · COM · 29384C108 · shares: $29,854,949
- PHARVARIS N V · COM · N69605108 · shares: $27,581,008
- CAMP4 THERAPEUTICS CORP · COM · 13463J101 · shares: $25,647,928
- ARTIVA BIOTHERAPEUTICS INC · COM · 04317A107 · shares: $22,827,049
- TECTONIC THERAPEUTIC INC · COM · 878972108 · shares: $20,853,938
- ZENTALIS PHARMACEUTICALS INC · COM · 98943L107 · shares: $19,147,378
- CELLDEX THERAPEUTICS INC NEW · COM NEW · 15117B202 · shares: $18,503,417
- EYEPOINT INC · COM NEW · 30233G209 · shares: $15,015,000
Reported holdings
16 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| MAPLIGHT THERAPEUTICS INC | COM | 56565P103 | — | 950,011 shares | $34,048,394 |
| TYRA BIOSCIENCES INC | COM | 90240B106 | — | 1,029,298 shares | $32,875,778 |
| ENTRADA THERAPEUTICS INC | COM | 29384C108 | — | 4,056,379 shares | $29,854,949 |
| PHARVARIS N V | COM | N69605108 | — | 797,600 shares | $27,581,008 |
| CAMP4 THERAPEUTICS CORP | COM | 13463J101 | — | 5,869,091 shares | $25,647,928 |
| ARTIVA BIOTHERAPEUTICS INC | COM | 04317A107 | — | 2,353,304 shares | $22,827,049 |
| TECTONIC THERAPEUTIC INC | COM | 878972108 | — | 606,660 shares | $20,853,938 |
| ZENTALIS PHARMACEUTICALS INC | COM | 98943L107 | — | 3,947,913 shares | $19,147,378 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | — | 497,270 shares | $18,503,417 |
| EYEPOINT INC | COM NEW | 30233G209 | — | 1,050,000 shares | $15,015,000 |
| BIOHAVEN LTD | COM | G1110E107 | — | 738,972 shares | $10,995,903 |
| SURROZEN INC | COM NEW | 86889P208 | — | 271,250 shares | $7,038,938 |
| SKYE BIOSCIENCE INC | COM NEW | 83086J200 | — | 9,681,763 shares | $6,712,366 |
| ALX ONCOLOGY HLDGS INC | COM | 00166B105 | — | 3,057,325 shares | $6,328,663 |
| PROTARA THERAPEUTICS INC | COM STK | 74365U107 | — | 1,369,782 shares | $5,232,567 |
| SILENCE THERAPEUTICS PLC | ADS | 82686Q101 | — | 476,200 shares | $5,228,676 |