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ARCH Venture Management, LLC

Period ended Jun 30, 2026 · Latest filing Aug 14, 2026

These quarterly holdings are delayed and may not include all assets or short positions. Values are from the reporting date, not current prices or purchase costs. The same security may appear in multiple rows.

Source: SEC

Reported portfolio value

Quarter-end reported holdings; not current value or investment performance.

View reported values
  • Jun 30, 2026: $1,100,261,770

More quarters will appear as history becomes available.

Top holdings

Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.

View top holdings values
  1. PARABILIS MEDICINES INC · COM · 698955101 · shares: $175,517,789
  2. BEAM THERAPEUTICS INC · COM · 07373V105 · shares: $155,771,929
  3. RAPPORT THERAPEUTICS INC · COM · 75383L102 · shares: $155,376,512
  4. SEAPORT THERAPEUTICS INC · COMMON STOCK · 81221K108 · shares: $136,600,437
  5. ERASCA INC · COM · 29479A108 · shares: $129,917,324
  6. VIR BIOTECHNOLOGY INC · COM · 92764N102 · shares: $129,353,521
  7. MAZE THERAPEUTICS INC · COM · 578784100 · shares: $122,983,582
  8. LYELL IMMUNOPHARMA INC · COM NEW · 55083R203 · shares: $45,525,211
  9. GENERATE BIOMEDICINES INC · COM SHS · 370920100 · shares: $32,802,467
  10. 10X GENOMICS INC · CL A COM · 88025U109 · shares: $8,351,756

Reported holdings

12 reported entries
IssuerClassCUSIPTypeShares / principalReported value (USD)
PARABILIS MEDICINES INCCOM698955101 — 6,412,780 shares $175,517,789
BEAM THERAPEUTICS INCCOM07373V105 — 4,540,132 shares $155,771,929
RAPPORT THERAPEUTICS INCCOM75383L102 — 3,728,738 shares $155,376,512
SEAPORT THERAPEUTICS INCCOMMON STOCK81221K108 — 6,294,951 shares $136,600,437
ERASCA INCCOM29479A108 — 7,091,557 shares $129,917,324
VIR BIOTECHNOLOGY INCCOM92764N102 — 12,694,163 shares $129,353,521
MAZE THERAPEUTICS INCCOM578784100 — 4,120,053 shares $122,983,582
LYELL IMMUNOPHARMA INCCOM NEW55083R203 — 3,247,162 shares $45,525,211
GENERATE BIOMEDICINES INCCOM SHS370920100 — 1,944,426 shares $32,802,467
10X GENOMICS INCCL A COM88025U109 — 217,834 shares $8,351,756
BOUNDLESS BIO INCCOM10170A100 — 2,694,095 shares $6,735,238
GOSSAMER BIO INCCOM38341P102 — 8,055,916 shares $1,326,004