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DAFNA Capital Management LLC
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $524,358,409
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- REVOLUTION MEDICINES INC · COM · 76155X100 · shares: $105,369,346
- SPDR S&P BIOTECH ETF · ETF · 78464A870 · shares: $31,096,916
- COMPASS PATHWAYS PLC · SPONSORED ADS · 20451W101 · shares: $28,469,121
- STEREOTAXIS INC · COM NEW · 85916J409 · shares: $23,530,553
- NEKTAR THERAPEUTICS · COM NEW · 640268306 · shares: $22,226,108
- DENALI THERAPEUTICS INC · COM · 24823R105 · shares: $19,007,440
- IDEAYA BIOSCIENCES INC · COM · 45166A102 · shares: $18,532,135
- ATRICURE INC · COM · 04963C209 · shares: $16,716,119
- XENON PHARMACEUTICALS INC · COM · 98420N105 · shares: $15,136,598
- CYTOKINETICS INC · COM NEW · 23282W605 · shares: $14,652,510
Reported holdings
88 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| REVOLUTION MEDICINES INC | COM | 76155X100 | — | 562,630 shares | $105,369,346 |
| SPDR S&P BIOTECH ETF | ETF | 78464A870 | — | 196,505 shares | $31,096,916 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 | — | 2,011,952 shares | $28,469,121 |
| STEREOTAXIS INC | COM NEW | 85916J409 | — | 13,680,554 shares | $23,530,553 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 | — | 318,380 shares | $22,226,108 |
| DENALI THERAPEUTICS INC | COM | 24823R105 | — | 739,014 shares | $19,007,440 |
| IDEAYA BIOSCIENCES INC | COM | 45166A102 | — | 497,240 shares | $18,532,135 |
| ATRICURE INC | COM | 04963C209 | — | 597,431 shares | $16,716,119 |
| XENON PHARMACEUTICALS INC | COM | 98420N105 | — | 250,772 shares | $15,136,598 |
| CYTOKINETICS INC | COM NEW | 23282W605 | — | 171,998 shares | $14,652,510 |
| ARCUS BIOSCIENCES INC | COM | 03969F109 | — | 441,829 shares | $13,621,588 |
| ASCENDIS PHARMA A/S | ORD SHS | K08588103 | — | 48,469 shares | $12,927,652 |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | — | 57,769 shares | $9,736,098 |
| AXOGEN INC | COM | 05463X106 | — | 208,960 shares | $9,651,862 |
| INSULET CORP | COM | 45784P101 | — | 61,870 shares | $9,419,708 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | — | 226,819 shares | $9,215,656 |
| BICARA THERAPEUTICS INC | COM | 055477103 | — | 284,955 shares | $8,460,314 |
| ISHARES NASDAQ BIOTECH INDX | ETF | 464287556 | — | 42,595 shares | $8,101,143 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | — | 335,255 shares | $7,328,674 |
| MAPLIGHT THERAPEUTICS INC | COM | 56565P103 | — | 171,006 shares | $6,128,855 |
| LARIMAR THERAPEUTICS INC | COM | 517125100 | — | 2,008,164 shares | $6,124,900 |
| CENTURY THERAPEUTICS INC | COM | 15673T100 | — | 2,400,458 shares | $5,881,122 |
| DEXCOM INC | COM | 252131107 | — | 86,279 shares | $5,810,891 |
| IMMUNOVANT INC | COM | 45258J102 | — | 149,524 shares | $5,761,160 |
| INOGEN INC | COM | 45780L104 | — | 845,179 shares | $5,451,405 |
| TANDEM DIABETES CARE INC | COM | 875372203 | — | 355,208 shares | $5,360,089 |
| ALKERMES PLC | SHS | G01767105 | — | 101,266 shares | $5,305,832 |
| STOKE THERAPEUTICS INC | COM | 86150R107 | — | 130,875 shares | $4,282,230 |
| ALLOGENE THERAPEUTICS INC | COM | 019770106 | — | 2,000,000 shares | $4,160,000 |
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | — | 400,248 shares | $4,002,480 |
| LAKEFRONT BIOTHERAPEUTICS NV | SPON ADR | 36315X101 | — | 130,175 shares | $3,902,647 |
| ORTHOPEDIATRICS CORP | COM | 68752L100 | — | 189,130 shares | $3,618,057 |
| CYBIN INC | COM NEW | 23256X407 | — | 514,061 shares | $3,397,943 |
| RAPPORT THERAPEUTICS INC | COM | 75383L102 | — | 75,000 shares | $3,125,250 |
| KYMERA THERAPEUTICS INC | COM | 501575104 | — | 27,000 shares | $3,096,090 |
| PROQR THERAPEUTICS NV | SHS EURO | N71542109 | — | 1,530,361 shares | $2,846,471 |
| NEUROGENE INC | COM | 64135M105 | — | 89,032 shares | $2,800,056 |
| ADLAI NORTYE LTD | SPONSORED ADS | 00704R109 | — | 239,553 shares | $2,754,860 |
| PROCEPT BIOROBOTICS CORP | COM | 74276L105 | — | 120,000 shares | $2,709,600 |
| AQUESTIVE THERAPEUTICS INC | COM | 03843E104 | — | 645,915 shares | $2,687,006 |
| CELLDEX THERAPEUTICS INC | COM NEW | 15117B202 | — | 68,518 shares | $2,549,555 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | — | 46,500 shares | $2,495,655 |
| ALIGN TECHNOLOGY INC | COM | 016255101 | — | 14,000 shares | $2,361,240 |
| VIKING THERAPEUTICS INC | COM | 92686J106 | — | 59,516 shares | $2,321,719 |
| NERVGEN PHARMA CORP | COM | 64082X203 | — | 1,050,000 shares | $2,163,000 |
| BIOHAVEN LTD | COM | G1110E107 | — | 137,593 shares | $2,047,384 |
| MAZE THERAPEUTICS INC | COM | 578784100 | — | 65,000 shares | $1,939,600 |
| ALECTOR INC | COM | 014442107 | — | 908,351 shares | $1,825,786 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 | — | 377,059 shares | $1,755,210 |
| PROFOUND MEDICAL CORP | COM NEW | 74319B502 | — | 260,360 shares | $1,731,394 |
| ATRIUM THERAPEUTICS INC | COM | 04965N104 | — | 128,000 shares | $1,721,600 |
| ANNEXON INC | COM | 03589W102 | — | 297,812 shares | $1,700,507 |
| CYTOMX THERAPEUTICS INC | COM | 23284F105 | — | 438,407 shares | $1,644,026 |
| ULTRAGENYX PHARMACEUTICAL INC | COM | 90400D108 | — | 47,100 shares | $1,572,669 |
| EUPRAXIA PHARMACEUTICALS INC | COM | 29842P105 | — | 225,600 shares | $1,491,216 |
| DESIGN THERAPEUTICS INC | COM | 25056L103 | — | 102,600 shares | $1,484,622 |
| FATE THERAPEUTICS INC | COM | 31189P102 | — | 525,000 shares | $1,417,500 |
| MEDIWOUND LTD | SHS NEW | M68830112 | — | 94,405 shares | $1,387,754 |
| KURA ONCOLOGY INC | COM | 50127T109 | — | 120,568 shares | $1,322,631 |
| ARS PHARMACEUTICALS INC | COM | 82835W108 | — | 164,285 shares | $1,315,923 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 | — | 44,490 shares | $1,200,340 |
| IMMATICS NV | SHS | N44445109 | — | 116,960 shares | $1,184,805 |
| TELA BIO INC | COM | 872381108 | — | 1,441,029 shares | $1,080,772 |
| POLYPID LTD | COM | M8001Q126 | — | 207,900 shares | $1,056,132 |
| CORBUS PHARMACEUTICALS HLDGS | COM NEW | 21833P301 | — | 107,773 shares | $1,010,911 |
| INSPIRE MEDICAL SYSTEMS INC | COM | 457730109 | — | 18,200 shares | $811,902 |
| ADICET BIO INC | COM NEW | 007002207 | — | 93,812 shares | $810,536 |
| SEAPORT THERAPEUTICS INC | COMMON STOCK | 81221K108 | — | 32,400 shares | $703,728 |
| MBX BIOSCIENCES INC | COM | 55287L101 | — | 11,809 shares | $651,857 |
| BIONTECH SE | SPONSORED ADS | 09075V102 | — | 7,000 shares | $651,350 |
| ARTIVA BIOTHERAPEUTICS INC | COM | 04317A107 | — | 67,101 shares | $650,880 |
| PLIANT THERAPEUTICS INC | COM | 729139105 | — | 487,000 shares | $555,180 |
| SCYNEXIS INC | COM | 811292309 | — | 135,868 shares | $552,983 |
| EDITAS MEDICINE INC | COM | 28106W103 | — | 170,470 shares | $552,323 |
| ORCHESTRA BIOMED HOLDINGS INC | COM | 68572M106 | — | 126,841 shares | $547,319 |
| FOGHORN THERAPEUTICS INC | COM | 344174107 | — | 111,859 shares | $545,872 |
| ACCURAY INC | COM | 004397105 | — | 1,680,508 shares | $433,235 |
| Q32 BIO INC | COM | 746964105 | — | 32,896 shares | $419,095 |
| NUVECTIS PHARMA INC | COM | 67080T108 | — | 20,000 shares | $367,800 |
| COMPUGEN LTD | ORD | M25722105 | — | 168,232 shares | $360,016 |
| IBIO INC | COM NEW | 451033708 | — | 170,053 shares | $297,593 |
| AUTOLUS THERAPEUTICS LTD | SPON ADS | 05280R100 | — | 179,316 shares | $286,906 |
| BICYCLE THERAPEUTICS PLC | SPONSORED ADS | 088786108 | — | 64,492 shares | $273,446 |
| TENAYA THERAPEUTICS INC | COM | 87990A106 | — | 300,000 shares | $221,730 |
| VERRICA PHARMACEUTICALS INC | COM SHS | 92511W207 | — | 23,750 shares | $145,350 |
| ENGENE THERAPEUTICS INC | COM | 29286X101 | — | 74,650 shares | $129,145 |
| KARDIGAN INC | COM | 485925101 | — | 5,000 shares | $119,250 |
| ADC THERAPEUTICS SA | SHS | H0036K147 | — | 77,081 shares | $82,477 |