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HighVista Strategies LLC

Period ended Jun 30, 2026 · Latest filing Aug 14, 2026

These quarterly holdings are delayed and may not include all assets or short positions. Values are from the reporting date, not current prices or purchase costs. The same security may appear in multiple rows.

Source: SEC

Reported portfolio value

Quarter-end reported holdings; not current value or investment performance.

View reported values
  • Jun 30, 2026: $438,599,158

More quarters will appear as history becomes available.

Top holdings

Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.

View top holdings values
  1. INVESCO DB COMMDY INDX TRCK · UNIT · 46138B103 · shares: $28,185,965
  2. ABIVAX SA · SPONSORED ADS · 00370M103 · shares: $15,062,511
  3. REVOLUTION MEDICINES INC · COM · 76155X100 · shares: $12,544,576
  4. DEFINIUM THERAPEUTICS INC · COM SHS · 24477V105 · shares: $11,425,263
  5. IMMUNOVANT INC · COM · 45258J102 · shares: $10,706,447
  6. PRAXIS PRECISION MEDICINES I · COM NEW · 74006W207 · shares: $10,114,006
  7. RELAY THERAPEUTICS INC · COM · 75943R102 · shares: $9,471,675
  8. ALKERMES PLC · SHS · G01767105 · shares: $9,392,118
  9. VAXCYTE INC · COM · 92243G108 · shares: $8,704,329
  10. TANGO THERAPEUTICS INC · COM · 87583X109 · shares: $8,129,788

Reported holdings

147 reported entries
IssuerClassCUSIPTypeShares / principalReported value (USD)
INVESCO DB COMMDY INDX TRCKUNIT46138B103 — 1,057,238 shares $28,185,965
ABIVAX SASPONSORED ADS00370M103 — 113,031 shares $15,062,511
REVOLUTION MEDICINES INCCOM76155X100 — 66,983 shares $12,544,576
DEFINIUM THERAPEUTICS INCCOM SHS24477V105 — 242,884 shares $11,425,263
IMMUNOVANT INCCOM45258J102 — 277,873 shares $10,706,447
PRAXIS PRECISION MEDICINES ICOM NEW74006W207 — 30,210 shares $10,114,006
RELAY THERAPEUTICS INCCOM75943R102 — 506,235 shares $9,471,675
ALKERMES PLCSHSG01767105 — 179,256 shares $9,392,118
VAXCYTE INCCOM92243G108 — 149,739 shares $8,704,329
TANGO THERAPEUTICS INCCOM87583X109 — 260,070 shares $8,129,788
LIQUIDIA CORPORATIONCOM NEW53635D202 — 97,896 shares $7,805,248
COGENT BIOSCIENCES INCCOM19240Q201 — 188,780 shares $7,305,786
STRUCTURE THERAPEUTICS INCSPONSORED ADS86366E106 — 130,784 shares $7,019,177
ENLIVEN THERAPEUTICS INCCOM29337E102 — 137,866 shares $6,996,700
AMYLYX PHARMACEUTICALS INCCOM03237H101 — 386,080 shares $6,933,997
SPYRE THERAPEUTICS INCCOM NEW00773J202 — 77,807 shares $6,907,706
LB PHARMACEUTICALS INCCOM SHS50180M108 — 211,511 shares $6,864,590
CYTOKINETICS INCCOM NEW23282W605 — 78,003 shares $6,645,076
C4 THERAPEUTICS INCCOM STK12529R107 — 1,348,136 shares $6,295,800
TYRA BIOSCIENCES INCCOM90240B106 — 184,774 shares $5,901,681
ALUMIS INCCOM022307102 — 199,968 shares $5,627,100
PHARVARIS N VCOMN69605108 — 160,494 shares $5,549,882
TARSUS PHARMACEUTICALS INCCOM87650L103 — 87,060 shares $5,479,557
COMPASS PATHWAYS PLCSPONSORED ADS20451W101 — 371,120 shares $5,251,349
DIANTHUS THERAPEUTICS INCCOM252828108 — 51,125 shares $4,983,665
NURIX THERAPEUTICS INCCOM67080M103 — 203,739 shares $4,942,709
AXSOME THERAPEUTICS INC.COM05464T104 — 20,183 shares $4,940,193
TRAVERE THERAPEUTICS INCCOM89422G107 — 86,233 shares $4,898,896
VERA THERAPEUTICS INCCL A92337R101 — 105,907 shares $4,544,470
NVIDIA CORPORATIONCOM67066G104 — 21,792 shares $4,360,361
GH RESEARCH PLCORDINARY SHARESG3855L106 — 158,770 shares $4,267,737
PALISADE BIO INCCOM696389402 — 2,030,927 shares $4,244,638
ARGENX SESPONSORED ADR04016X101 — 4,561 shares $4,231,559
MAZE THERAPEUTICS INCCOM578784100 — 136,572 shares $4,075,308
OCULAR THERAPEUTIX INCCOM67576A100 — 408,534 shares $4,011,804
ORUKA THERAPEUTICS INCCOM687604108 — 41,902 shares $3,987,813
DYNE THERAPEUTICS INCCOM26818M108 — 171,961 shares $3,819,254
EDGEWISE THERAPEUTICS INCCOM28036F105 — 90,996 shares $3,697,168
MOONLAKE IMMUNOTHERAPEUTICSCLASS A ORD61559X104 — 187,946 shares $3,659,308
INSMED INCCOM PAR $.01457669307 — 31,256 shares $3,332,515
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B202 — 86,964 shares $3,235,930
AMAZON COM INCCOM023135106 — 13,397 shares $3,193,041
INVENTIVA SAADS46124U107 — 831,442 shares $3,142,851
TALEN ENERGY CORPCOM87422Q109 — 8,148 shares $3,130,951
RELMADA THERAPEUTICS INCCOM75955J402 — 445,799 shares $3,084,929
PROTAGONIST THERAPEUTICS INCCOM74366E102 — 24,460 shares $2,998,307
ERASCA INCCOM29479A108 — 160,328 shares $2,937,208
VIRIDIAN THERAPEUTICS INCCOM92790C104 — 159,885 shares $2,937,087
HEWLETT PACKARD ENTERPRISE CCOM42824C109 — 59,081 shares $2,665,143
MINERALYS THERAPEUTICS INCCOM603170101 — 86,085 shares $2,322,573
GUARDANT HEALTH INCCOM40131M109 — 15,419 shares $2,313,313
AVALO THERAPEUTICS INCCOM NEW05338F306 — 122,610 shares $2,265,832
JAMES HARDIE INDS PLCORD SHSG4253H101 — 85,198 shares $2,230,484
EYEPOINT INCCOM NEW30233G209 — 155,704 shares $2,226,567
MASTEC INCCOM576323109 — 5,137 shares $2,137,300
XENON PHARMACEUTICALS INCCOM98420N105 — 35,318 shares $2,131,795
RBC BEARINGS INCCOM75524B104 — 3,223 shares $2,075,805
VISA INCCOM CL A92826C839 — 5,961 shares $2,045,160
ASSEMBLY BIOSCIENCES INCCOM NEW045396207 — 73,405 shares $2,017,170
STOKE THERAPEUTICS INCCOM86150R107 — 61,316 shares $2,006,260
OLEMA PHARMACEUTICALS INCCOM68062P106 — 160,167 shares $2,003,689
ROCKET COS INCCOM CL A77311W101 — 125,530 shares $1,977,098
XPO INCCOM983793100 — 9,623 shares $1,975,506
WESTERN DIGITAL CORPCOM958102105 — 3,050 shares $1,948,096
CORE SCIENTIFIC INC NEWCOM21874A106 — 75,712 shares $1,937,470
TEXAS INSTRS INCCOM882508104 — 6,500 shares $1,937,455
KBR INCCOM48242W106 — 54,206 shares $1,871,733
FLOWSERVE CORPCOM34354P105 — 24,958 shares $1,850,886
ALPHABET INCCAP STK CL C02079K107 — 5,127 shares $1,811,523
SEAGATE TECHNOLOGY HLDNGS PLORD SHSG7997R103 — 1,870 shares $1,804,550
MIRUM PHARMACEUTICALS INCCOM604749101 — 14,892 shares $1,743,407
DNOW INCCOM67011P100 — 132,900 shares $1,723,713
ON SEMICONDUCTOR CORPCOM682189105 — 18,200 shares $1,720,628
NUCOR CORPCOM670346105 — 7,600 shares $1,692,900
USA TODAY CO INCCOM36472T109 — 188,500 shares $1,611,675
BROADCOM INCCOM11135F101 — 4,199 shares $1,586,172
CALUMET INCCOM131428104 — 44,000 shares $1,584,880
QNITY ELECTRONICS INCCOMMON STOCK74743L100 — 9,700 shares $1,584,107
KODIAK SCIENCES INCCOM50015M109 — 40,590 shares $1,581,387
CREDO TECHNOLOGY GROUP HOLDIORDINARY SHARESG25457105 — 5,800 shares $1,577,310
KNIGHT-SWIFT TRANSN HLDGS INCL A499049104 — 20,100 shares $1,565,187
BRINKS COCOM109696104 — 16,414 shares $1,550,959
ASTERA LABS INCCOM04626A103 — 3,198 shares $1,544,698
S&P GLOBAL INCCOM78409V104 — 3,782 shares $1,540,257
MADRIGAL PHARMACEUTICALS INCCOM558868105 — 2,852 shares $1,531,381
EQUIFAX INCCOM294429105 — 9,572 shares $1,519,268
RHYTHM PHARMACEUTICALS INCCOM76243J105 — 13,657 shares $1,516,337
SAVARA INCCOM805111101 — 242,379 shares $1,493,054
DOMINOS PIZZA INCCOM25754A201 — 4,991 shares $1,477,536
BELITE BIO INCSPONSORED ADS07782B104 — 9,554 shares $1,471,173
MICRON TECHNOLOGY INCCOM595112103 — 1,260 shares $1,454,406
CIENA CORPCOM NEW171779309 — 2,925 shares $1,434,888
CELCUITY INCCOM15102K100 — 13,472 shares $1,409,440
QXO INCCOM NEW82846H405 — 81,420 shares $1,406,938
IMMUNOCORE HLDGS PLCADS45258D105 — 43,185 shares $1,371,125
CG ONCOLOGY INCCOM156944100 — 18,867 shares $1,340,500
US FOODS HLDG CORPCOM912008109 — 13,000 shares $1,329,250
TRANSDIGM GROUP INCCOM893641100 — 985 shares $1,312,059
LUMENTUM HLDGS INCCOM55024U109 — 1,517 shares $1,301,677
FIRSTENERGY CORPCOM337932107 — 26,100 shares $1,240,794