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Octagon Capital Advisors LP

Period ended Jun 30, 2026 · Latest filing Aug 14, 2026

These quarterly holdings are delayed and may not include all assets or short positions. Values are from the reporting date, not current prices or purchase costs. The same security may appear in multiple rows.

Source: SEC

Reported portfolio value

Quarter-end reported holdings; not current value or investment performance.

View reported values
  • Jun 30, 2026: $1,112,538,962

More quarters will appear as history becomes available.

Top holdings

Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.

View top holdings values
  1. DIANTHUS THERAPEUTICS INC · COM · 252828108 · shares: $179,525,699
  2. DEFINIUM THERAPEUTICS INC · COM SHS · 24477V105 · shares: $138,768,000
  3. ABIVAX SA · SPONSORED ADS · 00370M103 · shares: $132,327,180
  4. COGENT BIOSCIENCES INC · COM · 19240Q201 · shares: $90,945,000
  5. ALUMIS INC · COM · 022307102 · shares: $79,655,898
  6. ARRIVENT BIOPHARMA INC · COM · 04272N102 · shares: $68,474,416
  7. TAYSHA GENE THERAPIES INC · COM SHS · 877619106 · shares: $66,010,992
  8. BIOAGE LABS INC · COM · 09077V100 · shares: $42,843,480
  9. MIRUM PHARMACEUTICALS INC · COM · 604749101 · shares: $39,675,023
  10. KYMERA THERAPEUTICS INC · COM · 501575104 · shares: $35,547,700

Reported holdings

27 reported entries
IssuerClassCUSIPTypeShares / principalReported value (USD)
DIANTHUS THERAPEUTICS INCCOM252828108 — 1,841,667 shares $179,525,699
DEFINIUM THERAPEUTICS INCCOM SHS24477V105 — 2,950,000 shares $138,768,000
ABIVAX SASPONSORED ADS00370M103 — 993,000 shares $132,327,180
COGENT BIOSCIENCES INCCOM19240Q201 — 2,350,000 shares $90,945,000
ALUMIS INCCOM022307102 — 2,830,700 shares $79,655,898
ARRIVENT BIOPHARMA INCCOM04272N102 — 1,971,054 shares $68,474,416
TAYSHA GENE THERAPIES INCCOM SHS877619106 — 9,693,244 shares $66,010,992
BIOAGE LABS INCCOM09077V100 — 1,748,000 shares $42,843,480
MIRUM PHARMACEUTICALS INCCOM604749101 — 338,900 shares $39,675,023
KYMERA THERAPEUTICS INCCOM501575104 — 310,000 shares $35,547,700
AKTIS ONCOLOGY INCCOM01021M104 — 960,847 shares $30,968,099
XENON PHARMACEUTICALS INCCOM98420N105 — 490,000 shares $29,576,400
ERASCA INCCALL29479A908 CALL 1,255,000 shares $22,991,600
PALISADE BIO INCCOM696389402 — 10,276,317 shares $21,477,503
OCULAR THERAPEUTIX INCCOM67576A100 — 2,075,000 shares $20,376,500
DISC MEDICINE INCCOM254604101 — 270,000 shares $19,747,800
SUMMIT THERAPEUTICS INCCOM86627T108 — 1,250,000 shares $18,212,500
PHARVARIS N VCOMN69605108 — 456,721 shares $15,793,412
ADLAI NORTYE LTDSPONSORED ADS00704R109 — 934,716 shares $10,749,234
PRECISION BIOSCIENCES INCCOM NEW74019P207 — 1,350,000 shares $10,611,000
DBV TECHNOLOGIES S ASPONSORED ADS23306J309 — 574,200 shares $9,416,880
FAETH THERAPEUTICS INCCOM NEW81728A207 — 361,010 shares $9,025,250
GYRE THERAPEUTICS INCCOM403783103 — 954,416 shares $6,289,601
TREVI THERAPEUTICS INCCOM89532M101 — 315,000 shares $5,874,750
UNICYCIVE THERAPEUTICS INCCOM NEW90466Y202 — 1,000,000 shares $4,690,000
CONTEXT THERAPEUTICS INCCOM21077P108 — 3,050,000 shares $1,689,395
GOSSAMER BIO INCCOM38341P102 — 7,750,000 shares $1,275,650