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ORBIMED ADVISORS LLC
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $5,396,779,685
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- EDGEWISE THERAPEUTICS INC · COM · 28036F105 · shares: $630,516,330
- ENLIVEN THERAPEUTICS INC · COM · 29337E102 · shares: $343,914,074
- ELI LILLY & CO · COM · 532457108 · shares: $309,332,997
- MBX BIOSCIENCES INC · COM · 55287L101 · shares: $189,266,227
- SINOVAC BIOTECH LTD · SHS · P8696W104 · shares: $184,466,170
- ASTRAZENECA PLC · ORD · G0593M107 · shares: $171,079,502
- STRUCTURE THERAPEUTICS INC · SPONSORED ADS · 86366E106 · shares: $118,578,498
- SIONNA THERAPEUTICS INC · COM · 829401108 · shares: $112,433,029
- CORVUS PHARMACEUTICALS INC · COM · 221015100 · shares: $107,045,190
- ARRIVENT BIOPHARMA INC · COM · 04272N102 · shares: $105,169,375
Reported holdings
129 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| IMAGENEBIO INC | COM | 45175G207 | — | 909,269 shares | $5,364,687 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | — | 42,100 shares | $5,160,618 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | — | 17,000 shares | $5,117,510 |
| PALISADE BIO INC | COM | 696389402 | — | 2,333,000 shares | $4,875,970 |
| REVOLUTION MEDICINES INC | NOTE 0.500% 5/0 | 76155XAA8 | — | 3,500,000 principal | $4,379,725 |
| ATAIBECKLEY INC | COM SHS | 04650F101 | — | 797,500 shares | $4,202,825 |
| UNITEDHEALTH GROUP INC | COM | 91324P102 | CALL | 10,000 shares | $4,156,300 |
| PTC THERAPEUTICS INC | COM | 69366J200 | — | 49,100 shares | $4,005,087 |
| ARTIVION INC | COM | 228903100 | — | 175,000 shares | $3,932,250 |
| ELEVANCE HEALTH INC FORMERLY | COM | 036752103 | CALL | 10,000 shares | $3,867,300 |
| NEUMORA THERAPEUTICS INC. | COM | 640979100 | — | 2,139,882 shares | $3,637,799 |
| ACADIA PHARMACEUTICALS INC | COM | 004225108 | — | 137,000 shares | $3,466,100 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | — | 183,400 shares | $3,293,864 |
| TYRA BIOSCIENCES INC | COM | 90240B106 | — | 102,000 shares | $3,257,880 |
| RAPPORT THERAPEUTICS INC | COM | 75383L102 | — | 76,616 shares | $3,192,589 |
| AGOMAB THERAPEUTICS NV | SPONSORED ADS | 00860C102 | — | 192,740 shares | $2,501,765 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 | — | 35,581 shares | $2,239,468 |
| ACLARIS THERAPEUTICS INC | COM | 00461U105 | — | 421,500 shares | $2,229,735 |
| CYTOKINETICS INC | COM NEW | 23282W605 | — | 25,800 shares | $2,197,902 |
| INSPIREMD INC | COM | 45779A846 | — | 3,133,405 shares | $2,193,697 |
| OCULAR THERAPEUTIX INC | COM | 67576A100 | — | 220,000 shares | $2,160,400 |
| EVOMMUNE INC | COM SHS | 30054Y107 | — | 161,000 shares | $2,139,690 |
| BELITE BIO INC | SPONSORED ADS | 07782B104 | — | 13,300 shares | $2,048,001 |
| OVID THERAPEUTICS INC | COM | 690469101 | — | 747,000 shares | $2,009,430 |
| EUPRAXIA PHARMACEUTICALS INC | COM | 29842P105 | — | 269,000 shares | $1,778,090 |
| SELLAS LIFE SCIENCES GROUP I | COM NEW | 81642T209 | PUT | 92,500 shares | $1,365,300 |
| COGENT BIOSCIENCES INC | NOTE 1.625%11/1 | 19240QAA0 | — | 1,000,000 principal | $1,227,500 |
| VIRIDIAN THERAPEUTICS INC | NOTE 1.750% 5/1 | 92790CAB0 | — | 1,000,000 principal | $1,072,670 |
| TRAWS PHARMA INC | COM NEW | 68232V884 | — | 1,203,260 shares | $1,014,709 |