← Back to Discover
Paradigm Biocapital Advisors LP
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $5,340,558,034
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- REVOLUTION MEDICINES INC · COM · 76155X100 · shares: $1,191,348,571
- NUVALENT INC · COM · 670703107 · shares: $731,667,476
- EDGEWISE THERAPEUTICS INC · COM · 28036F105 · shares: $415,053,937
- GENMAB A/S · SPONSORED ADS · 372303206 · shares: $360,767,109
- SPYRE THERAPEUTICS INC · COM NEW · 00773J202 · shares: $340,984,271
- APOGEE THERAPEUTICS INC · COM · 03770N101 · shares: $209,233,581
- ORUKA THERAPEUTICS INC · COM · 687604108 · shares: $204,094,539
- TANGO THERAPEUTICS INC · COM · 87583X109 · shares: $198,736,169
- BELITE BIO INC · SPONSORED ADS · 07782B104 · shares: $189,844,565
- ERASCA INC · COM · 29479A108 · shares: $174,956,000
Reported holdings
28 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| REVOLUTION MEDICINES INC | COM | 76155X100 | — | 6,361,323 shares | $1,191,348,571 |
| NUVALENT INC | COM | 670703107 | — | 5,924,433 shares | $731,667,476 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | — | 10,215,455 shares | $415,053,937 |
| GENMAB A/S | SPONSORED ADS | 372303206 | — | 13,133,131 shares | $360,767,109 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | — | 3,840,778 shares | $340,984,271 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 | — | 1,576,385 shares | $209,233,581 |
| ORUKA THERAPEUTICS INC | COM | 687604108 | — | 2,144,526 shares | $204,094,539 |
| TANGO THERAPEUTICS INC | COM | 87583X109 | — | 6,357,523 shares | $198,736,169 |
| BELITE BIO INC | SPONSORED ADS | 07782B104 | — | 1,232,877 shares | $189,844,565 |
| ERASCA INC | COM | 29479A108 | — | 9,550,000 shares | $174,956,000 |
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 | — | 2,775,649 shares | $174,699,348 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | — | 480,000 shares | $144,494,400 |
| INSMED INC | COM PAR $.01 | 457669307 | — | 1,325,977 shares | $141,375,668 |
| MBX BIOSCIENCES INC | COM | 55287L101 | — | 2,508,015 shares | $138,442,428 |
| VAXCYTE INC | COM | 92243G108 | — | 2,127,852 shares | $123,692,037 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | — | 6,723,788 shares | $123,515,986 |
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 | — | 8,670,576 shares | $108,468,906 |
| JADE BIOSCIENCES INC | COM NEW | 008064206 | — | 2,857,405 shares | $63,491,539 |
| TYRA BIOSCIENCES INC | COM | 90240B106 | — | 1,828,607 shares | $58,405,708 |
| ASSEMBLY BIOSCIENCES INC | COM NEW | 045396207 | — | 1,553,748 shares | $42,696,995 |
| EYEPOINT INC | COM NEW | 30233G209 | — | 2,890,397 shares | $41,332,677 |
| ACHIEVE LIFE SCIENCE INC | COM | 004468500 | — | 4,951,856 shares | $32,335,620 |
| VOR BIOPHARMA INC | COM NEW | 929033207 | — | 1,750,000 shares | $32,217,500 |
| MAPLIGHT THERAPEUTICS INC | COM | 56565P103 | — | 685,852 shares | $24,580,936 |
| KARDIGAN INC | COM | 485925101 | — | 900,000 shares | $21,465,000 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 | — | 4,175,382 shares | $19,436,403 |
| EDITAS MEDICINE INC | COM | 28106W103 | — | 5,586,625 shares | $18,100,665 |
| INVENTIVA SA | ADS | 46124U107 | — | 4,000,000 shares | $15,120,000 |