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TCG Crossover Management, LLC
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $4,160,526,316
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- ABIVAX SA AMERICAN DEPOSITARY SHARES · COMM · 00370M103 · shares: $800,603,959
- TANGO THERAPEUTICS INC · COMM · 87583X109 · shares: $283,878,343
- CG ONCOLOGY INC · COMM · 156944100 · shares: $260,768,136
- COGENT BIOSCIENCES INC · COMM · 19240Q201 · shares: $187,866,673
- IMMUNOVANT INC · COMM · 45258J102 · shares: $171,766,278
- SPYRE THERAPEUTICS INC · COMM · 00773J202 · shares: $168,733,670
- DIANTHUS THERAPEUTICS INC · COMM · 252828108 · shares: $163,437,308
- MIRUM PHARMACEUTICALS INC · COMM · 604749101 · shares: $124,334,076
- ZAI LAB LTD-ADR · ADRS · 98887Q104 · shares: $116,614,913
- AMYLYX PHARMACEUTICALS INC · COMM · 03237H101 · shares: $112,138,864
Reported holdings
54 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| ABIVAX SA AMERICAN DEPOSITARY SHARES | COMM | 00370M103 | — | 6,007,834 shares | $800,603,959 |
| TANGO THERAPEUTICS INC | COMM | 87583X109 | — | 9,081,201 shares | $283,878,343 |
| CG ONCOLOGY INC | COMM | 156944100 | — | 3,670,206 shares | $260,768,136 |
| COGENT BIOSCIENCES INC | COMM | 19240Q201 | — | 4,854,436 shares | $187,866,673 |
| IMMUNOVANT INC | COMM | 45258J102 | — | 4,457,988 shares | $171,766,278 |
| SPYRE THERAPEUTICS INC | COMM | 00773J202 | — | 1,900,582 shares | $168,733,670 |
| DIANTHUS THERAPEUTICS INC | COMM | 252828108 | — | 1,676,624 shares | $163,437,308 |
| MIRUM PHARMACEUTICALS INC | COMM | 604749101 | — | 1,062,049 shares | $124,334,076 |
| ZAI LAB LTD-ADR | ADRS | 98887Q104 | — | 6,137,627 shares | $116,614,913 |
| AMYLYX PHARMACEUTICALS INC | COMM | 03237H101 | — | 6,243,812 shares | $112,138,864 |
| MONTE ROSA THERAPEUTICS INC | COMM | 61225M102 | — | 4,622,151 shares | $111,856,054 |
| BIOCRYST PHARMACEUTICALS INC | COMM | 09058V103 | — | 11,020,968 shares | $110,209,680 |
| VOR BIOPHARMA INC | COMM | 929033207 | — | 5,673,078 shares | $104,441,366 |
| TYRA BIOSCIENCES INC | COMM | 90240B106 | — | 3,248,980 shares | $103,772,421 |
| DYNE THERAPEUTICS INC | COMM | 26818M108 | — | 4,615,144 shares | $102,502,348 |
| DISC MEDICINE INC | COMM | 254604101 | — | 1,341,862 shares | $98,143,787 |
| RELAY THERAPEUTICS INC | COMM | 75943R102 | — | 4,273,356 shares | $79,954,491 |
| SAVARA INC | COMM | 805111101 | — | 12,362,205 shares | $76,151,183 |
| AURA BIOSCIENCES INC | COMM | 05153U107 | — | 9,533,333 shares | $67,686,664 |
| REVOLUTION MEDICINES INC | COMM | 76155X100 | — | 340,899 shares | $63,843,565 |
| FIRST TRACKS BIOTHERAPEUTICS | COMM | 337185102 | — | 2,895,304 shares | $58,253,516 |
| KODIAK SCIENCES INC | COMM | 50015M109 | — | 1,445,538 shares | $56,318,161 |
| AVALO THERAPEUTICS INC | COMM | 05338F306 | — | 3,017,120 shares | $55,756,378 |
| LB PHARMACEUTICALS INC | COMM | 50180M108 | — | 1,447,310 shares | $46,972,446 |
| CENTURY THERAPEUTICS INC | COMM | 15673T100 | — | 17,754,430 shares | $43,401,690 |
| TECTONIC THERAPEUTIC INC | COMM | 878972108 | — | 1,204,891 shares | $41,418,128 |
| XENCOR INC | COMM | 98401F105 | — | 2,452,138 shares | $39,479,422 |
| SURROZEN INC | COMM | 86889P208 | — | 1,473,101 shares | $38,226,971 |
| EDITAS MEDICINE INC | COMM | 28106W103 | — | 11,111,111 shares | $36,000,000 |
| MBX BIOSCIENCES INC | COMM | 55287L101 | — | 650,000 shares | $35,880,000 |
| PHARVARIS BV | COMM | N69605108 | — | 1,008,229 shares | $34,864,559 |
| SILENCE THERAPEUTICS PLC | ADRS | 82686Q101 | — | 3,033,560 shares | $33,308,489 |
| INFLARX N V | COMM | N44821101 | — | 14,500,000 shares | $32,480,000 |
| ALTIMMUNE INC | COMM | 02155H200 | — | 10,000,000 shares | $30,400,000 |
| JANUX THERAPEUTICS INC | COMM | 47103J105 | — | 1,789,617 shares | $27,488,517 |
| PERSPECTIVE THERAPEUTICS INC | COMM | 46489V302 | — | 7,915,567 shares | $26,992,083 |
| AGOMAB THERAPEUTICS NV | ADRS | 00860C102 | — | 2,053,233 shares | $26,650,964 |
| BIOHAVEN LTD | COMM | G1110E107 | — | 1,779,952 shares | $26,485,686 |
| AKTIS ONCOLOGY INC | COMM | 01021M104 | — | 696,560 shares | $22,450,129 |
| ALECTOR INC | COMM | 014442107 | — | 10,000,000 shares | $20,100,000 |
| FORTE BIOSCIENCES INC | COMM | 34962G208 | — | 920,000 shares | $19,550,000 |
| MONOPAR THERAPEUTICS INC | COMM | 61023L207 | — | 203,327 shares | $18,826,047 |
| OCULAR THERAPEUTIX INC | COMM | 67576A100 | — | 1,647,752 shares | $16,180,925 |
| ADC THERAPEUTICS SA | COMM | H0036K147 | — | 11,390,175 shares | $12,187,487 |
| ALX ONCOLOGY HOLDINGS INC | COMM | 00166B105 | — | 5,655,487 shares | $11,706,858 |
| ENTRADA THERAPEUTICS INC | COMM | 29384C108 | — | 1,060,230 shares | $7,803,293 |
| CULLINAN THERAPEUTICS INC | COMM | 230031106 | — | 406,786 shares | $7,407,573 |
| ARVINAS HOLDING CO LLC | COMM | 04335A105 | — | 707,098 shares | $5,875,984 |
| KORRO BIO INC | COMM | 500946108 | — | 416,301 shares | $5,486,847 |
| RESEARCH ALLIANCE CORP CL A | COMM | G75226103 | — | 500,000 shares | $5,350,000 |
| LEONABIO INC | COMM | 04746L203 | — | 464,398 shares | $4,267,818 |
| JATT II ACQUISITION CORP | COMM | G50765109 | — | 200,000 shares | $2,272,000 |
| CONTEXT THERAPEUTICS INC | COMM | 21077P108 | — | 2,682,696 shares | $1,485,945 |
| EIKON THERAPEUTICS INC | COMM | 282564103 | — | 37,902 shares | $494,621 |